短暂性脑缺血发作及小卒中早期进展的风险评估

被引：4

作者：

钟秀玲

刘勇林

肖卫民

陈仰昆

机构：

[1] 东莞市人民医院神经内科

来源：

中华脑科疾病与康复杂志(电子版) | 2014年 / 4卷 / 01期

关键词：

脑缺血发作,短暂性; 卒中; 早期进展; ABCD2-DI评分;

D O I：

暂无

中图分类号：

R743.3 [急性脑血管疾病（中风）];

学科分类号：

100204 [神经病学];

摘要：

目的分析短暂性脑缺血发作(TIA)及小卒中早期进展的危险因素。方法回顾性分析448例TIA或小卒中患者的入院资料,随访发病后7、30及90 d脑梗死发生率/复发率,通过Logistic回归分析TIA/小卒中随访期间新发脑梗死的危险因素。结果 TIA/小卒中患者7、30及90 d内新发脑梗死率分别为26.3%、30.1%、36.8%;直线回归分析显示ABCD2-DI评分与TIA/小卒中早期新发脑梗死呈正相关关系。Logistic回归分析TIA/小卒中患者7、30及90 d新发脑梗死的危险因素为:ABCD2-DI评分(OR值分别为2.23、3.03、5.24,P均<0.05);糖化血红蛋白(OR值分别为1.71、2.56、3.44,P均<0.05);双联抗血小板药物治疗(OR值分别为0.42、0.39、0.26,P均<0.01);高敏CRP与7 d内新发脑梗死的OR值为1.58,P<0.05。结论 ABCD2-DI评分、高敏CRP、糖化血红蛋白是TIA/小卒中患者早期进展的独立危险因素,使用双联抗血小板药物治疗可能是TIA/小卒中早期进展的保护因素。

引用

页码：8 / 12

页数：5

共 20 条

[1]

ABCD3评分评价短暂性脑缺血发作患者早期发生脑梗死的风险 [J].

舒敏 ;

章军建 .

华中科技大学学报(医学版), 2012, 41 (05) :607-610

[2]

血糖、糖化血红蛋白与急性缺血性脑血管病相关性探讨 [J].

杜更胜 ;

谢琼英 ;

盛建玲 .

中国医药科学, 2011, 1 (06) :93-94

[3]

ABCD2评分结合MRA对短暂性脑缺血发作后发生脑梗死的评估价值 [J].

刘宏顺 ;

王志红 ;

芮汉臣 ;

夏红 .

解放军医学杂志, 2010, 35 (11) :1388-1391

[4]

Low positive predictive value of the ABCD<sup>2</sup> score in emergency department transient ischaemic attack diagnoses: the South Western Sydney Transient Ischaemic Attack Study[J] D. Ghia;P. Thomas;D. Cordato;D. Epstein;R. G. Beran;C. Cappelen‐Smith;N. Griffith;I. Hanna;A. McDougall;S. J. Hodgkinson;J. M. Worthington Internal Medicine Journal 2012,

[5]

Guidelines for the preventive treatment of ischaemic stroke and TIA (I). Update on risk factors and life style[J] Neurología (English Edition) 2011,

[6]

Acute Perfusion and Diffusion Abnormalities Predict Early New MRI Lesions 1 Week After Minor Stroke and Transient Ischemic Attack[J] Negar Asdaghi;Bilal Hameed;Monica Saini;Thomas Jeerakathil;Derek Emery;Kenneth Butcher Stroke 2011,

[7]

Predi??o do risco de evento cerebrovascular após um enfarte agudo do miocárdio[J] Revista Portuguesa de Cardiologia 2011,

[8]

Addition of Brain Infarction to the ABCD2 Score (ABCD2I): A Collaborative Analysis of Unpublished Data on 4574 Patients[J] Matthew F. Giles;Greg W. Albers;Pierre Amarenco;Murat M. Arsava;Andrew Asimos;Hakan Ay;David Calvet;Shelagh Coutts;Brett L. Cucchiara;Andrew M. Demchuk;S. Claiborne Johnston;Peter J. Kelly;Anthony S. Kim;Julien Labreuche;Philippa C. Lavallee;Jean-Louis Mas;Aine Merwick;Jean Marc Olivot;Francisco Purroy;Wayne D. Rosamond;Rossella Sciolla;Peter M. Rothwell Stroke 2010,

[9]

Addition of brain and carotid imaging to the ABCD 2 score to identify patients at early risk of stroke after transient ischaemic attack: a multicentre observational study[J] áine Merwick;Gregory W Albers;Pierre Amarenco;Ethem M Arsava;Hakan Ay;David Calvet;Shelagh B Coutts;Brett L Cucchiara;Andrew M Demchuk;Karen L Furie;Matthew F Giles;Julien Labreuche;Philippa C Lavallée;Jean-Louis Mas;Jean Marc Olivot;Francisco Purroy;Peter M Rothwell;Jeffrey L Saver;órla C Sheehan;John P Stack;Cathal Walsh;P

[10]

Population-Based Study of ABCD2 Score; Carotid Stenosis; and Atrial Fibrillation for Early Stroke Prediction After Transient Ischemic Attack: The North Dublin TIA Study[J] Orla C. Sheehan;Lorraine Kyne;Lisa A. Kelly;Niamh Hannon;Michael Marnane;Aine Merwick;Patricia M.E. McCormack;Joseph Duggan;Alan Moore;Joan Moroney;Leslie Daly;Dawn Harris;Gillian Horgan;Emma B. Williams;Peter J. Kelly Stroke 2010,

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