血清超氧化物歧化酶与同型半胱氨酸水平与心血管疾病的相关性研究

被引:12
作者
王璐
赵美芸
张敏
任方
徐龙
李智
韩平
机构
[1] 同济大学附属杨浦医院检验科
关键词
心血管疾病; 超氧化物歧化酶; 同型半胱氨酸;
D O I
暂无
中图分类号
R54 [心脏、血管(循环系)疾病]; R446.1 [生物化学检验、临床检验];
学科分类号
摘要
目的研究血清超氧化物歧化酶(SOD)和同型半胱氨酸(HCY)水平与心血管疾病的相关性。方法选取选取2014年1~6月住院治疗的83例心血管病患者,按照疾病类型分为急性冠状动脉综合征(ACS)组、不稳定型心绞痛(UAP)组、动脉粥样硬化(AS)组;另选取同期体检健康者20例作为健康对照组。测定所有研究对象的血清SOD和HCY水平,并进行相关性分析。结果3种心血管疾病患者的血清SOD水平低于健康对照组,HCY水平高于健康对照组,差异均有统计学意义(P<0.05);与治疗前比较,ACS组与AS组患者治疗后血清SOD水平均升高,HCY水平均下降,差异均有统计学意义(P<0.05);且ACS组及AS组患者血清SOD与HCY水平均呈负相关(相关系数r分别为0.901、0.924,P<0.05)。结论血清SOD和HCY水平检测对ASC与AS的治疗和预后有重要的临床指导价值。
引用
收藏
页码:752 / 753
页数:2
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