滑膜炎在骨关节炎病情进展中的意义

被引：12

作者：

杨勐航

戴生明

机构：

[1] 第二军医大学长海医院风湿免疫科

来源：

中华风湿病学杂志 | 2010年 / 07期

关键词：

D O I：

暂无

中图分类号：

R684 [关节疾病及损伤];

学科分类号：

100220 [骨科学];

摘要：

<正>骨关节炎(osteoarthritis,OA)是一种与高龄、肥胖和创伤等多种危险因素有关的进行性、致残性疾病。以前认为OA的病理改变是关节软骨破坏,而近年来认识到,在OA的进展过程中,除了软骨以外,滑膜、骨质及关节囊均出现相应的病变,因而目前认为OA是一种全关节疾病。OA的发病机制也从之前认为的由关节软骨消耗磨损引起所谓退行性变所致,转而认为由软骨合成和分解代谢失调、机械磨损、局部炎症

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