复发性缺血性脑卒中的危险因素、严重程度及短期预后分析

被引:63
作者
田婷 [1 ]
关智媛 [2 ]
石正洪 [1 ]
栗静 [1 ]
冯斌 [1 ]
机构
[1] 兰州大学第二医院神经内科临床医学中心
[2] 兰州大学第二临床医学院
关键词
缺血性脑卒中; 复发; 危险因素; 美国国立卫生研究院卒中量表; 预后;
D O I
暂无
中图分类号
R743.3 [急性脑血管疾病(中风)];
学科分类号
摘要
目的探讨复发性缺血性脑卒中的危险因素,评价其严重程度及短期预后。方法 2014年3月2015年3月,本院复发性缺血性脑卒中患者238例(复发组),性别和年龄匹配的初发缺血性脑卒中患者378例(初发组)。比较两组患者的临床资料并进行非条件Logistic回归分析;对比两组患者入院和出院时美国国立卫生研究院卒中量表(NIHSS)评分及神经功能好转率。结果复发组脑白质疏松(χ2=8.666)、高血压(χ2=8.189)、吸烟(χ2=6.973)、饮酒(χ2=4.722)的发生率高于初发组(P<0.05)。Logistic回归分析显示,脑白质疏松(OR=1.690,95%CI:1.198~2.384,P=0.003)、高血压(OR=1.715,95%CI:1.135~2.592,P=0.010)、吸烟(OR=1.896,95%CI:1.233~2.915,P=0.004)是复发性缺血性脑卒中的独立危险因素。复发组入院及出院NIHSS评分均显著高于初发组(t=-3.645,t=-4.675,P<0.001),神经功能好转率明显低于初发组(t=2.643,P<0.01)。结论高血压、脑白质疏松、吸烟是复发性缺血性脑卒中的独立危险因素,复发性缺血性脑卒中患者较初发者病情严重,短期神经功能恢复慢。
引用
收藏
页码:172 / 177
页数:6
相关论文
共 18 条
  • [2] Types of stroke recurrence in patients with ischemic stroke: A substudy from the PRoFESS trial[J] . Danilo Toni,Emanuele Di Angelantonio,Maria Teresa Di Mascio,Richard Vinisko,Philip MW Bath.Int J Stroke . 2014 (7)
  • [3] Association of Leukoaraiosis with Stroke Recurrence Within 5 Years After Initial Stroke[J] . Emre Kumral,Halil Güllüo?lu,Naila Alakbarova,Bedriye Karaman,Emrah Emre Deveci,Ayd?n Bayramov,Dilek Evyapan,Figen G?k?ay,Mehmet Orman.Journal of Stroke and Cerebrovascular Diseases . 2014
  • [4] Lowering blood pressure to prevent stroke recurrence. A systematic review of long-term randomized trials[J] . Carlos A. Feldstein.Journal of the American Society of Hypertension . 2014
  • [5] Predictors of Stroke Recurrence in Patients with Recent Lacunar Stroke and Response to Interventions According to Risk Status: Secondary Prevention of Small Subcortical Strokes Trial[J] . Robert G. Hart,Lesly A. Pearce,Majid F. Bakheet,Oscar R. Benavente,Robin A. Conwit,Leslie A. McClure,Robert L. Talbert,David C. Anderson.Journal of Stroke and Cerebrovascular Diseases . 2014 (4)
  • [6] Smoking, Heart Rate, and Ischemic Stroke[J] . Tian Xu,Xiaoqing Bu,Hongmei Li,Mingzhi Zhang,Aili Wang,Weijun Tong,Tan Xu,Yingxian Sun,Yonghong Zhang.Stroke . 2013 (9)
  • [7] Association of Hypertension With Stroke Recurrence Depends on Ischemic Stroke Subtype
    Wang, Yilong
    Xu, Jie
    Zhao, Xingquan
    Wang, David
    Wang, Chunxue
    Liu, Liping
    Wang, Anxin
    Meng, Xia
    Li, Hao
    Wang, Yongjun
    [J]. STROKE, 2013, 44 (05) : 1232 - +
  • [8] Stroke and Stroke Care in China: Huge Burden, Significant Workload, and a National Priority[J] . Liping Liu,David Wang,K.S. Lawrence Wong,Yongjun Wang.Stroke . 2011 (12)
  • [9] Effects of Blood Pressure Lowering on Major Vascular Events Among Patients With Isolated Diastolic Hypertension: The Perindopril Protection Against Recurrent Stroke Study (PROGRESS) Trial*[J] . Hisatomi Arima,Craig Anderson,Teruo Omae,Mark Woodward,Jun Hata,Yoshitaka Murakami,Stephen MacMahon,Bruce Neal,John Chalmers.Stroke . 2011 (8)
  • [10] Risk and Cumulative Risk of Stroke Recurrence: A Systematic Review and Meta-Analysis[J] . Keerthi M. Mohan,Charles D.A. Wolfe,Anthony G. Rudd,Peter U. Heuschmann,Peter L. Kolominsky-Rabas,Andrew P. Grieve.Stroke A Journal of Cerebral Circulation . 2011 (5)