间充质干细胞在脓毒症治疗中的探索及机制

被引：2

作者：

吴振平 ^{[1
]}

张文苑 ^{[2
]}

沈佳聪 ^{[2
]}

张伦理 ^{[2
]}

方雪玲 ^{[1
]}

方强 ^{[1
]}

机构：

[1] 浙江大学医学院附属第一医院重症监护室, 杭州

[2] 南昌大学第一附属医院感染病科

来源：

中华传染病杂志 | 2019年 / 37卷 / 06期

关键词：

D O I：

暂无

中图分类号：

R459.7 [急症、急救处理];

学科分类号：

100231 [临床病理学];

摘要：

脓毒症是一种机体对感染反应失调所致的危及生命的器官功能障碍, 是重症监护室中常见的危重症。干细胞治疗具有减轻组织损伤、修复受伤组织的潜能, 同时具有良好的免疫调节和较强的抗炎及抗细胞凋亡能力。间充质干细胞在脓毒症治疗中取得了一些进展, 参与调节脓毒症时炎症因子表达、免疫细胞功能和组织修复再生等机制, 为探索脓毒症治疗带来了新希望。本文就间充质干细胞在脓毒症治疗中的作用机制、所面临的问题和未来展望做一综述。

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