脂连素——新型的脂源激素

[1] PPARgamma ligands increase expression and plasma concentrations of adiponectin, an adipose-derived protein. Maeda N,Takahashi M,Funahashi T et al. Diabetes . 2001

[2] Association of the T-G polymorphism in adiponectin (exon 2) with obesity and insulin sensitivity: interaction with family history of type 2 diabetes. Stumvoll M,Tschritter O,Fritsche A et al. Diabetes . 2002

[3] Synthetic peroxisome proliferator-activated receptor-gamma agonist, rosiglitazone,increases plasma levels of adiponectin in type 2 diabetic patients. Yang W S,Jeng C Y,Wu T J,et al. Diabetes Care . 2002

[4] Induction of adipocyte complementrelated protein of 30 kilodaltons by PPAR gamma agonists: a potential mechanism of insulin sensitization. Combs TP,Wagner JA,Berger J et al. The Journal of Endocrinology . 2002

[5] The adipocyte-derived protein Acrp30 enhances hepatic insulin action. Berg AH,Combs TP,Du X et al. Nature Medicine . 2001

[6] Effects of pioglitazone on metabolic parameters, body fat distribution, and serum adiponectin levels in Japanesemale patients with type 2 diabetes. Hirose H,Kawai T,Yamamoto Y et al. Metabolism . 2002

[7] Hypoadiponectinemia in obesity and type 2 diabetes: close association with insulin resistance and hyperinsulinemia. Weyer C,Funuhashi T,Tanaka S et al. The Journal of Clinical Endocrinology . 2001

[8] The fat-derived hormone adiponectin reverses insulin resistance with both lipoatrophy and obesity. Yamauchi T,Kamon J,Waki H et al. Nature Medicine . 2001

[9] Proteolytic cleavage product of 30-kDa adipocyte complement related protein increases fatty acid oxidation in muscle and causes weight loss in mice. Fruebis J,Tsao TS,Javorschi S,et al. Proceedings of the National Academy of Sciences of the United States of America . 2001

[10] Weight reduction increases plasma levels of an adipose-derived anti-inflammatory protein, adiponectin. Yang WS,Lee WJ,Funahashi T et al. The Journal of Clinical Endocrinology . 2001

[1] PPARgamma ligands increase expression and plasma concentrations of adiponectin, an adipose-derived protein. Maeda N,Takahashi M,Funahashi T et al. Diabetes . 2001

[2] Association of the T-G polymorphism in adiponectin (exon 2) with obesity and insulin sensitivity: interaction with family history of type 2 diabetes. Stumvoll M,Tschritter O,Fritsche A et al. Diabetes . 2002

[3] Synthetic peroxisome proliferator-activated receptor-gamma agonist, rosiglitazone,increases plasma levels of adiponectin in type 2 diabetic patients. Yang W S,Jeng C Y,Wu T J,et al. Diabetes Care . 2002

[4] Induction of adipocyte complementrelated protein of 30 kilodaltons by PPAR gamma agonists: a potential mechanism of insulin sensitization. Combs TP,Wagner JA,Berger J et al. The Journal of Endocrinology . 2002

[5] The adipocyte-derived protein Acrp30 enhances hepatic insulin action. Berg AH,Combs TP,Du X et al. Nature Medicine . 2001

[6] Effects of pioglitazone on metabolic parameters, body fat distribution, and serum adiponectin levels in Japanesemale patients with type 2 diabetes. Hirose H,Kawai T,Yamamoto Y et al. Metabolism . 2002

[7] Hypoadiponectinemia in obesity and type 2 diabetes: close association with insulin resistance and hyperinsulinemia. Weyer C,Funuhashi T,Tanaka S et al. The Journal of Clinical Endocrinology . 2001

[8] The fat-derived hormone adiponectin reverses insulin resistance with both lipoatrophy and obesity. Yamauchi T,Kamon J,Waki H et al. Nature Medicine . 2001

[9] Proteolytic cleavage product of 30-kDa adipocyte complement related protein increases fatty acid oxidation in muscle and causes weight loss in mice. Fruebis J,Tsao TS,Javorschi S,et al. Proceedings of the National Academy of Sciences of the United States of America . 2001

[10] Weight reduction increases plasma levels of an adipose-derived anti-inflammatory protein, adiponectin. Yang WS,Lee WJ,Funahashi T et al. The Journal of Clinical Endocrinology . 2001