引导骨再生屏障膜材料临床应用进展

被引：19

作者：

任立志 ^{[1
]}

孙睿 ^{[2
]}

机构：

[1] 山西医科大学口腔医学院·口腔医院口腔颌面外科

[2] 山西医科大学附属省人民医院口腔颌面外科

来源：

口腔疾病防治 | 2020年 / 28卷 / 06期

关键词：

引导性骨再生; 屏障膜; 生物活化性膜; 数字化3D打印钛网膜; 压电活性生物膜; 水平向骨增量; 垂直向骨增量;

D O I：

暂无

中图分类号：

R783.1 [牙科材料学];

学科分类号：

100301 [口腔基础医学];

摘要：

引导骨再生(guided bone regeneration,GBR)屏障膜对重建牙周组织的形态和功能具有重要意义。生物相容性、空间保持性、封闭性、可控性和生物活性是屏障膜应满足的主要标准。人工屏障膜生物材料可以分为合成高分子材料类、天然高分子材料类以及金属类,根据其降解特性分为可吸收与不可吸收两大类。用于水平向骨增量的GBR可以治疗多种类型的骨缺损,包括治疗骨开窗、骨开裂,使用不可吸收e-聚四氟乙烯(polytetrafluoroethylene,PTFE)膜或可吸收胶原膜都可以达到很好的预期效果。而对于牙槽嵴顶上增量或垂直向骨增量挑战性大,需要其有良好的强度,维持成骨空间,可以通过使用形态稳定的钛增强e-PTFE或d-PTFE膜,或者也可以使用钛板或钛网覆盖可吸收膜来实现垂直向的骨增量。目前生物活化性膜、数字化3D打印钛网膜、压电活性生物膜为研究热点,在未来的研究中会进一步提高膜的生物活化性,会推进人工膜研发进入下一个阶段。

引用

页码：404 / 408

页数：5

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