老年女性类风湿关节炎合并骨质疏松症的代谢特点分析

被引：7

作者：

范俊

郭洪佩

徐瑛

李燕

曹玉华

机构：

[1] 同济大学附属杨浦医院风湿科

来源：

现代生物医学进展 | 2014年 / 14卷 / 18期

关键词：

类风湿关节; 骨质疏松症; 骨密度;

D O I：

10.13241/j.cnki.pmb.2014.18.024

中图分类号：

R593.22 [类风湿性关节炎];

学科分类号：

100201 [内科学];

摘要：

目的:探讨老年女性类风湿关节炎(RA)合并骨质疏松症的代谢特点。方法:选择老年绝经后女性RA患者共59例,检测患者血生化代谢指标如血糖、血脂、CRP等和骨代谢指标如骨钙素(OC)、β-胶原特殊序列(β-Crosslaps)甲状旁腺素(iPTH)等,并进行统计分析。结果:骨质疏松患者的绝经时间、病程长度、OC、β-Crosslaps、iPTH显著高于骨量正常和骨量减少的患者,25羟基维生素D显著低于骨量正常和骨量减少的患者(P均<0.05)。RA患者的骨密度水平与是否使用激素和X线分期情况无关。结论:老年女性RA患者易发生骨质疏松,出现骨质疏松的RA女性患者绝经时间更长,可出现脂代谢紊乱及明显的维生素D缺乏,并具有高转换型骨代谢特点。

引用

页码：3493 / 3496

页数：4

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