经静脉心肌声学造影定量心肌缺血的实验研究

被引：5

作者：

苏伟

贾满盈

刘伊丽

黄晓波

查道刚

陈小林

谢晋国

黄铮

宾建平

机构：

[1] 南方医院心内科!广州市,南方医院心内科!广州市,南方医院心内科!广州市,南方医院心内科!广州市,南方医院心内科!广州市,南方医院心内科!广州市,南方医院心内科!广州市,南方医院心内科!广州市,南方医院心内科!广州市

来源：

第一军医大学学报 | 1997年 / 04期

关键词：

静脉心肌声学造影; 心肌缺血; C3F8声振白蛋白微泡悬液;

D O I：

暂无

中图分类号：

R445.1 [超声波诊断];

学科分类号：

100207 ;

摘要：

为评价经静脉心肌声学造影（MCE）定量心肌缺血（MI）的能力，在开胸犬动物模型上经静脉注射C3F8声振白蛋白微泡悬液，观察基础状态下心肌酶谱、血流动力学等指标变化；观察在基础状态下和在LAD血流减少50％、减少75％及减少90％状态下MCE的时间－强度曲线变化。结果显示：峰强度、曲线下面积在各种状态下差别显著，且与冠脉血流是显著正相关，而达峰时间、峰强减半时间及至峰强减半时间与冠脉血流灌注是负相关，但不够敏感。C3F8声学造影剂不导致血流动力学指标改变，心肌酶谱、生化指标于注射造影剂前后也无明显改变；心电图ST－T无改变，无心律失常。结论：静脉注射C3F8声振白蛋白微泡悬液行MCE可定量心肌缺血，且安全可靠。

引用

页码：296 / 298

页数：3

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