共 16 条
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The rationale and strategy used to develop a series of highly potent, irreversible, inhibitors of the epidermal growth factor receptor family of tyrosine kinases. Bridges AJ. Current Medicinal Chemistry . 1999
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erbB receptor-induced activation of stat transcription factors is mediated by Src tyrosine kinases. Olayioye MA,Beuvink I,Horsch K,et al. Journal of Biological Chemistry . 1999
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The erbB signaling network: receptor heterodimerization in development and cancer. Olayioye MA,Neve RM,Lane HA,et al. EMBO Journal . 2000
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C-erbB-3 in human breast carcinoma: expression and related to prognosis and established prognostic indicators. Travis A,Pinder SE,Robert JFR,et al. British Journal of Cancer . 1996
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The tumor suppression activity of E1A in HER-2/neu-overexpressing breast cancer. Chang JY,Xia W,Shao R,et al. Oncegene . 1997
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erbB-2, the preferred heterodimerization partner of all erbB receptors, is a mediator of lateral signaling. Graus Porta D,Beerli RR,Daly JM,et al. EMBO Journal . 1997
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erbB-2 is necessary for induction of carcinoma cell invasion by erbB family receptor tyrosine kinases. Spencer KSR,Graus Porta D,Leng J,et al. The Journal of Cell Biology . 2000
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Soluble and matrix-associated heparan sulfate proteoglycans increase expression of erbB-2 and erbB3 in colon cancer cell lines. Zvibel I,Brill S,Halpern Z,et al. International Journal of Cancer . 2001
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Tyrosine kinase inhibitors, emodin and its derivative repress Her-2/Neu-induced cellular transformation and metastasis-associated properties. Zhang LS,Lau YK,Xi L,et al. Oncegene . 1998
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Expression of the cerbB-4/HER4 protein and mRNA in normal human fetal and adult tissues and in a survey of nine sold tumor types. Srinivasan R,Poulson R,Hurst HC,et al. Journal of Paleopathology . 1998