含硒化合物研究进展

被引:24
作者
郭利
恽榴红
机构
[1] 军事医学科学院毒物药物研究所!北京
关键词
硒; 硒蛋白; 含硒化合物; 新药;
D O I
暂无
中图分类号
R965 [实验药理学];
学科分类号
100602 ; 100706 ;
摘要
硒是一种重要的食物源抗氧化剂 ,在体内以硒代半胱氨酸形式参与谷胱甘肽过氧化物酶、碘化甲腺原氨酸脱碘酶等多种蛋白质的形成 ,具有重要的生理学作用。含硒化合物具有多种药理活性 ,HoMePAESe是第 1个口服有效的含硒抗高血压药物 ,ebselen已作为缺血性卒中的治疗药物进入Ⅲ期临床 ,其他还有抗炎、抗癌等多种含硒化合物在研究之中
引用
收藏
页码:155 / 158
页数:4
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