p27基因和蛋白表达的调控及其在肿瘤发生机制中的作用

被引:6
作者
张欣
张志刚
机构
[1] 复旦大学上海医学院病理系
关键词
p27; 细胞周期; 肿瘤;
D O I
暂无
中图分类号
R730.2 [肿瘤病理学、病因学];
学科分类号
100214 ;
摘要
p27-kip1基因编码的P27蛋白作为细胞周期蛋白依赖性激酶抑制剂,在细胞周期进程中起重要的负调节作用,同时作为一个新的肿瘤抑制基因,与肿瘤的发生、发展及预后密切相关,近年来调节P27机制的新发现为肿瘤治疗开辟了新的道路。
引用
收藏
页码:170 / 174
页数:5
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