药物代谢酶单核苷酸多态性与异烟肼致肝损害研究现状

被引：6

作者：

刘芳

申阿东

机构：

[1] 首都医科大学附属北京儿童医院北京市儿科研究所儿科学国家重点学科省部共建儿科重大疾病研究重点实验室

来源：

中国循证儿科杂志 | 2011年 / 6卷 / 05期

关键词：

D O I：

暂无

中图分类号：

R725.9 [小儿全身性疾病];

学科分类号：

100201 [内科学];

摘要：

<正>2000年,中国流行病学调查数据显示,全国结核杆菌感染率约为44.5%,其中0～14岁儿童的结核杆菌感染率为9.0%,活动性肺结核患病率约为91.8/10万[1]。20世纪50年代,异烟肼(INH)曾被认为安全、无不良反应,但在20世纪70年代初,研究人员发现大量由INH引起的肝损

引用

页码：395 / 400

页数：6

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