成人呼吸窘迫综合征(ARDS)发生机制的实验研究

被引:2
作者
罗正曜
尤家騄
肖惠清
孔桂英
陈广文
机构
[1] 湖南医学院病理生理学教研组
关键词
肺非呼吸功能; 白细胞; 血小板; 油酸损伤肺; 狗;
D O I
暂无
中图分类号
学科分类号
摘要
本文用油酸静脉注射引起狗实验性RDS,并用Wu Hoak测量血中血小板微聚物的方法对肺的非呼吸功能进行了研究。结果发现,肺解除血中微聚物的功能(非呼吸功能)受损发生在呼吸功能(PaO2)受损之前,同时血中白细胞及血小板急剧减少。文中对此机制进行了讨论。本文资料对临床ARDS早期诊断提供了有益的线索。
引用
收藏
页码:115 / 121
页数:7
相关论文
共 6 条
[1]  
Early detection of oxygen-induced lung injury in consciou s rabbits. Dobuler KJ,et al. The American Review of Respiratory Disease . 1982
[2]  
Embolic pneumopathy induced by oleic acid. Derks CM,et al. American Journal of Pathology . 1976
[3]  
Complement-induced granulocyte aggregate. Jacob HS,et al. The New England Journal of Medicine . 1980
[4]  
Pulmonary platelet deposition accompanying acute oleic acid induced pulmonary injury. Spragg RG,et al. The American Review of Respiratory Disease . 1982
[5]  
Oxygen radical mediated endothelial damage by complement-stimulated granulocyte. Sack T,et al. The Journal of Clinical Investigation . 1978
[6]  
A new method for the quantitative determination of platelet aggregates. Wu KK,et al. The Lancet . 1974