Calpain与心肌细胞凋亡

被引：9

作者：

李明辉

陈瑞珍

机构：

[1] 复旦大学附属中山医院,上海市心血管病研究所,卫生部病毒性心脏病重点实验室

来源：

中国病理生理杂志 | 2009年 / 25卷 / 07期

关键词：

卡配因; 心肌细胞; 细胞凋亡;

D O I：

暂无

中图分类号：

R363 [病理生理学];

学科分类号：

100103 [病原生物学];

摘要：

Cardiomyocytes apoptosis plays a crucial role in the pathologic process of some ischemic and non-ischemic heart diseases. Since the discovery of the calpain family,more and more studies have demonstrated their close relationship with cell apoptosis. In addition to the consideration of their unique distribution in the cardiomyocytes,we are enthralled by their implication of a novel direction for both the diagnosis and the treatment of various heart diseases.

引用

页码：1438 / 1440+1450 +1450

页数：4

共 8 条

[1]

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Kameyama, Masaki .

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2007, 364 (02) :372-377

[2]

Calpain-Mediated Impairment of Na+/K+–ATPase Activity During Early Reperfusion Contributes to Cell Death After Myocardial Ischemia.[J].Javier Inserte;David Garcia-Dorado;Victor Hernando;Jordi Soler-Soler.Circulation Research.2005, 5

[3]

Calpain cleavage regulates the protein stability of p73 [J].