治疗阿尔茨海默病新药盐酸美金刚

被引:25
作者
罗京京
何玲
刘国卿
机构
[1] 中国药科大学药理教研室
关键词
盐酸美金刚; 阿尔茨海默病; NMDA受体阻滞剂; 学习记忆;
D O I
暂无
中图分类号
R971 [神经系统药物];
学科分类号
摘要
N-甲基-D-天门冬氨酸(NMDA)受体阻滞剂盐酸美金刚是FDA批准的第1个用于治疗中、重度阿尔茨海默病(Alzheimer's disease,AD)的药物,主要通过调节脑内谷氨酸水平发挥作用。临床研究表明,盐酸美金刚是一种安全、有效,且较有市场前景的药物,单用或与多奈哌齐联用都有明显的治疗作用;口服20 mg·d-1对中、重度AD患者的认知、行为能力等方面都有明显改善。
引用
收藏
页码:742 / 744
页数:3
相关论文
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