氨氯地平/阿托伐他汀的固定剂量复合制剂——多达一

被引：17

作者：

吴平生

陶宇

机构：

[1] 南方医科大学南方医院心内科

来源：

中国新药杂志 | 2010年 / 19卷 / 18期

关键词：

多达一; 氨氯地平; 阿托伐他汀; 抗动脉粥样硬化; 药理学; 临床试验;

D O I：

暂无

中图分类号：

R944 [剂型];

学科分类号：

100702 [药剂学];

摘要：

氨氯地平/阿托伐他汀(多达一)是一种固定剂量复方制剂,其组分为二氢吡啶类钙离子通道阻滞剂苯磺酸氨氯地平和HMG-CoA还原酶抑制剂阿托伐他汀钙。多达一不仅能有效地控制高血压和血脂异常两个重要的危险因素,而且在抗氧化应激、改善NO释放和小动脉顺应性方面具有协同作用,更好地保护内皮功能,适用于高血压合并血脂异常的治疗或高血压合并多个危险因素患者心血管疾病的预防。复方制剂与单方片剂具有良好的生物等效性和安全性。多达一服药方便,显著提高依从性和治疗连续性,从而增加临床疗效。

引用

页码：1637 / 1641+1647 +1647

页数：6

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