高分辨CT研究支气管哮喘气道壁厚度与肺功能、病情严重度的相关性

被引:5
作者
张建
刘荣惠
刘文亚
楼俭茹
赵艳萍
机构
[1] 新疆医科大学第一附属医院呼吸科
[2] 新疆医科大学第一附属医院影像中心
[3] 新疆医科大学第一附属医院影像中心 新疆乌鲁木齐
[4] 新疆乌鲁木齐
关键词
支气管哮喘; 体层摄影术,X线计算机; 气道壁厚度; 肺功能;
D O I
暂无
中图分类号
R816.4 [胸部及呼吸系];
学科分类号
1001 ; 100105 ; 100207 ; 100602 ;
摘要
目的 :用高分辨CT(HRCT)扫描测量支气管哮喘患者段及亚段水平气道壁的厚度 ,评估与肺功能、病情严重度相关性。方法 :用HRCT扫描哮喘患者 36例 ,并测量能显示支气管横截面的内径为 1.5~ 6mm的气道壁的内外径、内外腔面积 ,通过公式计算出气道壁厚度与外径之比 (T/D) ;气道壁面积占气道总横截面积百分比 (WA % ) ,评估T/D、WA %与肺功能、病情严重度的相关性。结果 :WA %与支气管哮喘病情严重度呈正相关 (r =0 .10 8,P =0 .0 15 ) ,与用力呼气中段流速 (FEF2 5~ 75% )呈负相关 (r =- 0 .114 ,P =0 .0 4 1)。结论 :HRCT可测定气道壁厚度 ,评估哮喘患者气道重构 ;哮喘患者气道壁厚度随病情加重及肺功能减退逐渐增加。
引用
收藏
页码:498 / 500
页数:3
相关论文
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