A lot of progresses in understanding of the production and effects of NO have been made in recent years. Large number of studies showed that NO play an important role in the pathogenesis of septic shock. Some other investigators reported that NOS inhibitors could have the potential therapeutic value in septic shock treatment.
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Effects of NO on blood flow distribution and oxygen extraction capabilities during endotoxic shock..Zhang H; Rogiers P; Smail N; et al;.J Appl Physiol.1997,
Effects of NO on blood flow distribution and oxygen extraction capabilities during endotoxic shock..Zhang H; Rogiers P; Smail N; et al;.J Appl Physiol.1997,