病原细菌多糖疫苗和多糖结合疫苗研究进展

被引：8

作者：

潘超

朱力

王恒樑

机构：

[1] 军事医学科学院生物工程研究所,病原微生物生物安全国家重点实验室

来源：

生物技术通讯 | 2013年 / 24卷 / 05期

关键词：

多糖疫苗; 多糖结合疫苗; 病原细菌;

D O I：

暂无

中图分类号：

R392.1 [免疫生物学];

学科分类号：

摘要：

在许多病原细菌中,荚膜多糖和O抗原多糖能够刺激机体产生保护性抗体,因此利用病原细菌的多糖制成的疫苗能有效预防传染病,同时避免了病原细菌耐药性的出现。此类疫苗包括多糖疫苗和多糖结合疫苗。细菌体内糖基化的发现,使得利用生物法生产多糖结合疫苗成了多糖结合疫苗生产的热门方向。我们简要综述了多糖疫苗和多糖结合疫苗在研究和应用方面的主要进展。

引用

页码：705 / 709

页数：5

共 11 条

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