年龄和性别因素对缺血性脑卒中的影响研究进展

被引：46

作者：

王雷

熊晓星

简志宏

机构：

[1] 武汉大学人民医院神经外科

来源：

国际神经病学神经外科学杂志 | 2017年 / 44卷 / 01期

关键词：

缺血性脑卒中; 年龄; 性别; 性激素; 炎症反应; 预后;

D O I：

10.16636/j.cnki.jinn.2017.01.025

中图分类号：

R743.3 [急性脑血管疾病（中风）];

学科分类号：

100204 [神经病学];

摘要：

缺血性脑卒中患者中年龄和性别因素对缺血性脑卒中的预后有着深远影响。衰老加重缺血性脑卒中患者的预后。缺血性卒中患者在幼年及大于30岁人群中男性占多数。脑卒中事件中"雄性易患"现象可能与卵巢激素的保护作用有关。性别和与之有关的性激素对脑卒中的预后有重要影响。我们将讨论缺血性脑卒中的年龄和性别差异,为临床制定更有效的诊断方法和治疗措施提供帮助。

引用

页码：106 / 109

页数：4

共 24 条

[1]

Genetics of ischemic stroke: An Indian scenario [J].

Kumar, Amit ;

Kumar, Pradeep ;

Kathuria, Prachi ;

Misra, Shubham ;

Pandit, Awadh Kishor ;

Chakravarty, Kamalesh ;

Prasad, Manya .

NEUROLOGY INDIA, 2016, 64 (01) :29-37

[2]

2015 American Heart Association/American Stroke Association Focused Update of the 2013 Guidelines for the Early Management of Patients With Acute Ischemic Stroke Regarding Endovascular Treatment A Guideline for Healthcare Professionals From the American Heart Association/American Stroke Association [J].

Powers, William J. ;

Derdeyn, Colin P. ;

Biller, Jose ;

Coffey, Christopher S. ;

Hoh, Brian L. ;

Jauch, Edward C. ;

Johnston, Karen C. ;

Johnston, S. Claiborne ;

Khalessi, Alexander A. ;

Kidwell, Chelsea S. ;

Meschia, James F. ;

Ovbiagele, Bruce ;

Yavagal, Dileep R. .

STROKE, 2015, 46 (10) :3020-3035

[3]

Estrogen Signaling in Metabolic Inflammation.[J].Rosário Monteiro;Diana Teixeira;Concei??o Calhau;Dmitri V. Krysko.Mediators of Inflammation.2014,

[4]

Lewis, Danielle K. ;

Thomas, Kristen T. ;

Selvamani, Amutha ;

Sohrabji, Farida .

NEUROBIOLOGY OF AGING, 2012, 33 (06) :1123.e1-1123.e16

[5]

Effects of Chronic and Acute Oestrogen Replacement Therapy in Aged Animals after Experimental Stroke [J].

Liu, F. ;

Benashski, S. E. ;

Xu, Y. ;

Siegel, M. ;

McCullough, L. D. .

JOURNAL OF NEUROENDOCRINOLOGY, 2012, 24 (02) :319-330

[6]

Executive Summary: Heart Disease and Stroke Statistics-2012 Update A Report From the American Heart Association [J].

Roger, Veronique L. ;

Go, Alan S. ;

Lloyd-Jones, Donald M. ;

Benjamin, Emelia J. ;

Berry, Jarett D. ;

Borden, William B. ;

Bravata, Dawn M. ;

Dai, Shifan ;

Ford, Earl S. ;

Fox, Caroline S. ;

Fullerton, Heather J. ;

Gillespie, Cathleen ;

Hailpern, Susan M. ;

Heit, John A. ;

Howard, Virginia J. ;

Kissela, Brett M. ;

Kittner, Steven J. ;

Lackland, Daniel T. ;

Lichtman, Judith H. ;

Lisabeth, Lynda D. ;

Makuc, Diane M. ;

Marcus, Gregory M. ;

Marelli, Ariane ;

Matchar, David B. ;

Moy, Claudia S. ;

Mozaffarian, Dariush ;

Mussolino, Michael E. ;

Nichol, Graham ;

Paynter, Nina P. ;

Soliman, Elsayed Z. ;

Sorlie, Paul D. ;

Sotoodehnia, Nona ;

Turan, Tanya N. ;

Virani, Salim S. ;

Wong, Nathan D. ;

Woo, Daniel ;

Turner, Melanie B. .

CIRCULATION, 2012, 125 (01) :188-197

[7]

Expression of Na–K–Cl cotransporter and edema formation are age dependent after ischemic stroke.[J].Fudong Liu;Padmastuti Akella;Sharon E. Benashski;Yan Xu;Louise D. McCullough.Experimental Neurology.2010, 2

[8]

Age and Energy Intake Interact to Modify Cell Stress Pathways and Stroke Outcome [J].