天然来源HIV进入抑制剂的研究进展

被引:9
作者
杨洁
孙魏
刘叔文
机构
[1] 南方医科大学药学院
关键词
艾滋病; HIV进入抑制剂; 天然产物; 抗HIV药物;
D O I
暂无
中图分类号
R512.91 [获得性免疫缺陷综合征(AIDS艾滋病)];
学科分类号
100201 [内科学];
摘要
当前艾滋病的治疗为高效抗逆转录病毒疗法,使用的药物主要为逆转录酶抑制剂和蛋白酶抑制剂,但效果并不十分令人满意。HIV进入抑制剂通过阻止HIV进入靶细胞抑制病毒感染,是抗HIV新药研究中最活跃的领域之一。由于天然产物具有来源广泛、结构多样、有效和低毒等特点,使天然来源HIV进入抑制剂成为近年来研究和开发新型抗HIV药物的热点。对近年来天然来源HIV进入抑制剂的研究进行综述。
引用
收藏
页码:1837 / 1840
页数:4
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