离子液体反胶团中青霉素酰化酶的水解反应特性

被引：3

作者：

夏寒松

余江

刘会洲

机构：

[1] 中国科学院过程工程研究所分离科学与工程实验室

[2] 生化工程国家重点实验室

[3] 生化工程国家重点实验室北京

[4] 中国科学院研究生院

[5] 北京

来源：

化工学报 | 2005年 / 10期

关键词：

离子液体; 反胶团; 青霉素酰化酶; 青霉素水解反应; 6-氨基青霉烷酸;

D O I：

暂无

中图分类号：

TQ465.1 [青霉素及其衍生物];

学科分类号：

100705 ;

摘要：

Penicillin hydrolysis by penicillin acylase was carried out in reversed micelle with [C14mim]Cl ionic liquids. The experi ment indicated that this catalytic reaction showed better performance in enzymat ic solubility, activity and stability than the reaction in reversed micelle with cetyl trimethyl ammonium bromide （CTAB）. For example, the maximum solubility of penicillin acylase in ionic liquids system was twice more than that in CTAB, an d the maximal enzymatic activity in ionic liquids was 1.3 times than that in CT AB.The outstanding properties of ionic liquids, including low charge density and irregular sharpness of head ring,might be attributable to its distinct head gro up. Ionic liquids made it possible to optimize the enzymatic catalysis in rever sed micelle through altering its interfacial structure effectively.

引用

页码：1932 / 1935

页数：4