肿瘤相关巨噬细胞在结直肠癌转移及治疗中的作用

被引:8
作者
田慧香 [1 ]
马婕群 [2 ]
张彦兵 [2 ]
左倩倩 [1 ]
廖子君 [2 ]
机构
[1] 西安医学院
[2] 西安交通大学医学院附属陕西省肿瘤医院内一科
关键词
结直肠癌; 肿瘤相关巨噬细胞; 治疗策略;
D O I
暂无
中图分类号
R735.34 [];
学科分类号
摘要
肿瘤相关巨噬细胞(TAMs)在许多恶性肿瘤的发生、发展、侵袭及转移中发挥着重要作用,与肿瘤患者的预后密切相关。结直肠癌是我国发病率、死亡率均较高的恶性肿瘤,早期结直肠癌患者术后预后较好,但仍有部分患者出现复发和转移,TAMs被证实参与结直肠癌的进展和转移。TAMs作为新的治疗靶标,已成为肿瘤免疫治疗领域的研究热点。但在结直肠癌方面还未达到理想的效果,需要进一步深入研究,以期为结直肠癌患者的治疗提供新方法,延长患者的生存时间。
引用
收藏
页码:498 / 502+507 +507
页数:6
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