轻度认知功能障碍患者的神经心理学研究

被引:26
作者
王延平 [1 ]
李海员 [2 ]
杨少青 [1 ]
黄绍宽 [2 ]
邓永萍 [2 ]
陈智超 [2 ]
陈盛强 [1 ]
徐桂兰 [1 ]
机构
[1] 广州医学院第二附属医院神经内科
[2] 广州市老人院
关键词
轻度认知功能障碍; 神经心理学; 蒙特利尔认知评估量表;
D O I
暂无
中图分类号
R749.1 [脑器质性精神障碍];
学科分类号
摘要
目的探讨轻度认知功能障碍(MCI)患者神经心理学的特点。方法对42例MCI患者和55例健康对照者进行多项神经心理学检查,包括简易精神状态检查量表(MMSE)、蒙特利尔认知评估量表(MoCA)、临床痴呆评定量表(CDR)、语言流畅性测验(RVR)、韦氏智力测验(WAIS-RC)[包括数字广度测验(DS)、积木测验(BD)、相似性测验]、韦氏记忆测验(WMS-R)(包括逻辑记忆、联想学习、视觉再认、图片回忆)、日常生活能力量表(ADL),比较2组患者上述量表评分和MMSE、MoCA量表各亚项评分的差异。结果与对照者比较,MCI患者MMSE、MoCA总分和RVR、WAIS-RC、WMS-R分测验,MoCA量表各亚项(地点定向力除外),MMSE量表中计算与注意、延迟回忆两亚项评分较低,差异均有统计学意义(P<0.05)。结论 MCI患者不仅记忆受损,其计算与注意力、命名、视空间结构能力、执行功能也可受损,尤以延迟回忆、计算与注意力受损明显。MoCA涵盖了重要的认知领域,能较全面评估MCI患者的认知功能,值的临床推广应用。
引用
收藏
页码:412 / 415
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