肠道微生态对肝脏疾病的影响研究现状

被引：8

作者：

刘华

韩涛

机构：

[1] 天津市第三中心医院天津市人工细胞重点实验室天津市肝胆疾病研究所

来源：

武警后勤学院学报(医学版) | 2016年 / 25卷 / 04期

关键词：

肠道微生态; 肝疾病; 免疫; 综述;

D O I：

10.16548/j.2095-3720.2016.04.024

中图分类号：

R575 [肝及胆疾病];

学科分类号：

100201 [内科学];

摘要：

肠道作为人体巨大的细菌库,其微生态系统复杂多变。通过肝肠轴,肠道和肝脏不仅在解剖和功能上密切相连,两者的免疫也息息相关。近年来,肠道微生态与肝病免疫关联的研究也越来越受到重视。肠道微生态与肝脏疾病的免疫往往互为因果,肠道微生态失衡,通过病原体相关分子模式和损伤分子模式导致肝脏免疫激活从而肝病发生与进展;反之,肝脏疾病免疫反应也破坏肠道微生态。深入研究肠道微生态与肝脏疾病免疫的关系,为通过肠道微生态的调控对肝脏疾病免疫影响提供新的治疗思路与方向。

引用

页码：332 / 336

页数：5

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