气相色谱法测定人血浆中的利多卡因、布比卡因、普鲁卡因和丁卡因

被引:12
作者
解大建
刘亚平
谢荣
机构
[1] 北京医科大学临床医学研究所麻醉学研究室
关键词
普鲁卡因; 奴佛卡因; 局部麻醉药; 布比卡因; 丁哌卡因; 利多卡因; 昔罗卡因; 抗心律失常药; 丁卡因; 地卡因; 人血浆; 气相色谱法;
D O I
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中图分类号
学科分类号
摘要
本文将利多卡因、布比卡因、普鲁卡因和丁卡因四种局麻药分为酰胺类和酯类二个组,同类药物互为内标,用气相色谱法进行了血药浓度的测定。利多卡因、布比卡因、普鲁卡因和丁卡因的平均回收率和标准差分别为103.79±9.73%、90.18±6.90%、92.52±6.70%、101.04±8.00%,检测限度均小于0.5μg/ml。
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页码:275 / 277
页数:3
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