蒙特利尔认知评估量表与简易精神状态量表用于筛查血管性认知障碍的比较

被引:48
作者
张彦红 [1 ]
梁伟雄 [2 ]
朱磊 [2 ]
尤劲松 [3 ]
机构
[1] 广州市第一人民医院
[2] 广州中医药大学
[3] 广东省中医院神经一科
关键词
血管性认知障碍; 血管性痴呆; 非痴呆型血管性认知障碍; 蒙特利尔认知评估表; 简易精神状态量表; 神经心理学评估;
D O I
暂无
中图分类号
R749.1 [脑器质性精神障碍];
学科分类号
摘要
目的:比较蒙特利尔认知评估量表(MoCA)和简易精神状态检查(MMSE)在筛查脑血管病患者中血管性认知障碍(VCI)及其最主要的亚型血管性痴呆(VaD)的能力。方法:对广东省中医院神经科门诊及住院治疗的127例脑血管病患者进行广泛的神经心理学测验,包括记忆力、执行能力、注意力、视空间、语言等五个方面的内容,并进行MoCA量表和MMSE量表的评价。根据广泛的神经心理学评价结果,采用可操作性的方法诊断认知受损,由临床医生结合认知受损的结果及相应的诊断标准进一步诊断非痴呆型血管性认知障碍(VCIND)和VaD,以此诊断结果作为相对的临床金标准,绘制受试者工作曲线(ROC),比较Mo-CA量表和MMSE量表在筛查脑血管病患者中VC(I包括VCIND和VaD)及VaD的能力。结果:127例受试者中诊断为认知受损的共101例,进一步诊断为VaD患者55例,VCIND患者46例,诊断为认知正常的患者26例。结论:MoCA量表、MMSE量表在筛查脑血管患者中VCI患者时曲线下面积(AUC)比较,MoCA(0.956±0.0177)>MMSE(0.920±0.0233),Z=2.339,P=0.019;而在筛查脑血管病患者中VaD患者时AUC比较,MoCA(0.945±0.0194)与MMSE(0.931±0.0248)无显著性差异,Z=1.453,P=0.146。MOCA量表在筛查脑血管病患者中VCI患者时优于MMSE量表,而两量表在筛查脑血管病患者中VaD患者时能力相似。
引用
收藏
页码:431 / 436
页数:6
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