MELD相关评分体系对乙型肝炎相关慢加急性肝衰竭患者预后的预测价值

被引：21

作者：

林贤丰 ^{[1
]}

李凌菲 ^{[1
]}

俞燮琰 ^{[1
]}

肖冬冬 ^{[1
]}

吴圣杰 ^{[1
]}

陈黎黎 ^{[2
,3
]}

宋梅 ^{[2
,3
]}

刘文悦 ^{[1
]}

施可庆 ^{[2
,3
]}

陈永平 ^{[2
,3
]}

郑明华 ^{[2
,3
]}

机构：

[1] 温州医学院第一临床学院

[2] 温州医学院附属第一医院感染内科

[3] 温州医学院肝病研究所

来源：

中华临床医师杂志(电子版) | 2012年 / 6卷 / 19期

关键词：

肝功能衰竭; 预后; 曲线下面积; MELD相关评分体系;

D O I：

暂无

中图分类号：

R575.3 [肝功能衰竭];

学科分类号：

100201 [内科学];

摘要：

目的比较分析MELD、MELD-Na、MELDNa、MESO、iMELD、UKELD六种MELD相关评分体系预测乙型肝炎相关慢加急性肝衰竭(ACHBLF)患者的预后。方法纳入温州医学院附属第一医院327例ACHBLF患者,分别计算各个MELD评分体系值,比较各评分系统在死亡组和生存组中的差异。通过受试者工作特征(ROC)曲线和曲线下面积(AUC)进行比较分析。结果死亡组MELD、MELD-Na、MELDNa、MESO、iMELD、UKELD值分别是29.2±5.6、37.1±12.6、31.1±5.1、26.4±13.8、57.6±23.3、72.8±27.5,虽高于生存组的27.1±6.1、36.3±13.8、29.2±5.8、27.0±16.7、56.1±29.8、70.2±21.4,但除MELD(P=0.02)和MELDNa(P=0.02)评分外,其余差异无统计学意义(P=0.374,P=0.745,P=0.639,P=0.375);各评分系统的AUC分别为0.630、0.556、0.609、0.537、0.555、0.530。结论除MELD和MELDNa评分可能有一定评判价值外,MELD相关评分体系总体上对预测ACHBLF的预后表现较差,无法对ACHBLF进行有效、准确的预测。

引用

页码：5853 / 5857

页数：5

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