鼻炎与支气管哮喘发病的关系

被引:5
作者
黄柳一 [1 ]
莫恩明 [1 ]
蒋小云 [1 ]
林爱华 [2 ]
机构
[1] 中山大学附属第一医院儿科
[2] 中山大学北校区流行病与统计学系
关键词
鼻炎; 哮喘; 危险因素; 儿童;
D O I
暂无
中图分类号
R725.6 [小儿呼吸系及胸部疾病];
学科分类号
100202 ;
摘要
目的探讨小儿鼻炎与支气管哮喘发病的关系。方法鼻炎患者130例分成2组,单纯鼻炎组60例,鼻炎并哮喘组70例,分析两组年龄、性别、既往湿疹史、毛细支气管炎史、吸烟家族史、哮喘家族史、变应原检测、外周血总IgE及嗜酸性粒细胞(EOS)计数等方面的差别。并用Logistic回归分析进一步确定鼻炎患者发生哮喘的危险因素。结果将两组比较,发现既往毛细支气管炎史、哮喘家族史、母亲哮喘及变应原屋尘、粉尘螨阳性在鼻炎并哮喘组中更多见。此外,外周血总IgE和EOS计数在鼻炎并哮喘组高于单纯鼻炎组。Logistic回归分析发现,外周血总IgE和EOS计数增高是鼻炎并哮喘的重要的危险因素。结论若鼻炎患者存在既往毛细支气管炎史、哮喘家族史、变应原检测阳性,尤其是外周血总IgE和EOS计数增高者,应视为哮喘的前驱表现,需及早防治。
引用
收藏
页码:210 / 211
页数:2
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