CD40/CD40L与冠状动脉粥样硬化性心脏病的研究进展

被引:4
作者
张月婷
董平栓
机构
[1] 河南科技大学第一附属医院心内科
关键词
CD40/CD40L; 可溶性CD40L; 冠状动脉粥样硬化性心脏病; 动脉粥样硬化;
D O I
暂无
中图分类号
R541.4 [冠状动脉(粥样)硬化性心脏病(冠心病)];
学科分类号
摘要
随着对CD40/CD40L及可溶性CD40L生物学功能的了解,近年来人们逐渐认识到CD40/CD40L在动脉粥样硬化形成及斑块破裂中的重要作用,阻断CD40/CD40L信号转导对防治冠状动脉粥样硬化性心脏病具有重要的理论和实用价值。本文综述CD40/CD40L与冠状动脉粥样硬化性心脏病及其防治的相关研究进展。
引用
收藏
页码:3051 / 3054
页数:4
相关论文
共 13 条
[1]   国产替罗非班治疗高危急性冠脉综合征的临床观察 [J].
董平栓 ;
杜来景 ;
王绍欣 ;
杨旭明 ;
李志娟 ;
方新历 .
中国心血管病研究, 2008, (04) :280-282
[2]   CD40-CD40L系统与斑块稳定性的相关性研究 [J].
陈朝婷 ;
冯向飞 ;
盛净 .
重庆医科大学学报, 2007, (07) :692-696
[3]   冠心病患者血清sCD40L和MMP-9的变化及相关性 [J].
李江 ;
赵水平 ;
彭道泉 ;
周宏年 .
中南大学学报(医学版), 2004, (05) :517-520
[4]   CD40 ligand enhances monocyte tissue factor expression and thrombin generation via oxidative stress in patients with hypercholesterolemia [J].
Sanguigni, V ;
Ferro, D ;
Pignatelli, P ;
Del Ben, M ;
Nadia, T ;
Saliola, M ;
Sorge, R ;
Violi, F .
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 2005, 45 (01) :35-42
[5]  
The effect of elevated serum soluble CD40 ligand on the prognostic value in patients with acute coronary syndromes[J] . Jin-Chuan Yan,Jian Zhu,Ling Gao,Zong-Gui Wu,Xian-Tao Kong,Ren-Qian Zong,Lin-Zen Zhan.Clinica Chimica Acta . 2004 (1)
[6]   Effect of rosiglitazone treatment on soluble CD40L in patients with type 2 diabetes and coronary artery disease [J].
Marx, N ;
Imhof, A ;
Froehlich, J ;
Siam, L ;
Ittner, J ;
Wierse, G ;
Schmidt, A ;
Maerz, W ;
Hombach, V ;
Koenig, W .
CIRCULATION, 2003, 107 (15) :1954-1957
[7]  
Cooperation Between Secretory Phospholipase A2 and TNF-Receptor Superfamily Signaling: Implications for the Inflammatory Response in Atherogenesis[J] . Lucía Fuentes,Marita Hernández,Francisco Jesús Fernández-Avilés,Mariano Sánchez Crespo,María Luisa Nieto.Circulation Research: Journal of the American Heart Association . 2002 (8)
[8]   Expression of CD40 in vascular smooth muscle cells and macrophages is associated with early development of human atherosclerotic lesions [J].
Bruemmer, D ;
Riggers, U ;
Holzmeister, J ;
Grill, M ;
Lippek, F ;
Settmacher, U ;
Regitz-Zagrosek, V ;
Fleck, E ;
Graf, K .
AMERICAN JOURNAL OF CARDIOLOGY, 2001, 87 (01) :21-27
[9]  
Macrophages, smooth muscle cells, endothelial cells, and T-cells express CD40 and CD40L in fatty streaks and more advanced human atherosclerotic lesions[J] . T. H?kkinen,K. Karkola,S. Yl?-Herttuala.Virchows Archiv . 2000 (4)
[10]   Induction and regulation of matrix metalloproteinase-12 by cytokines and CD40 signaling in monocyte/macrophages [J].
Wu, LH ;
Fan, JL ;
Matsumoto, S ;
Watanabe, T .
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2000, 269 (03) :808-815