射线对血管平滑肌细胞抑制作用的机制

被引：1

作者：

庄永志

王俊杰

机构：

[1] 北京大学第三医院肿瘤治疗中心!北京

来源：

国外医学(放射医学核医学分册) | 2001年 / 01期

关键词：

血管内照射; 再狭窄; 平滑肌细胞; 经皮穿刺冠状动脉成形术;

D O I：

暂无

中图分类号：

R730.5 [肿瘤治疗学];

学科分类号：

100214 ;

摘要：

血管腔内放疗预防经皮穿刺冠状动脉血管成形术 (PTCA)后再狭窄的临床应用取得了令人瞩目的疗效。人们认为 ,射线预防 PTCA后血管再狭窄主要是射线对血管平滑肌细胞产生的抑制作用 ,但是这种抑制作用的机制尚不十分清楚 ,目前认为最关键的因素是射线抑制了血管平滑肌细胞的迁移和增殖 ,凋亡在射线抑制再狭窄过程中所起的作用尚存在争议。在这个过程中 ,射线对巨噬细胞和多种细胞因子的抑制作用也逐步受到人们的重视。

引用

页码：27 / 30

页数：4

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