高密度脂蛋白预防冠心病发生的研究进展

被引：17

作者：

郭锦军

蔡久英

机构：

[1] 辽宁医学院附属第一医院心内科

来源：

中国心血管病研究 | 2008年 / 03期

关键词：

D O I：

暂无

中图分类号：

R541.4 [冠状动脉（粥样）硬化性心脏病（冠心病）];

学科分类号：

100201 [内科学];

摘要：

<正>脂质代谢异常是冠心病(CHD)最重要的危险因素之一。许多大规模临床研究已充分证明胆固醇特别是低密度脂蛋白胆固醇(LDL-C)在冠心病的发生发展中的重要作用,降低LDL-C能显著减少冠心病事件。近年来流行病学及大规模临床研究已经证实高密度脂蛋白(HDL)对动脉血

引用

页码：231 / 234

页数：4

共 8 条

[1]

升高高密度脂蛋白胆固醇干预的现状与展望.[J].赵水平;.中华心血管病杂志.2007, 02

[2]

Emerging therapies targeting high-density lipoprotein metabolism and reverse cholesterol transport [J].

Duffy, D ;

Rader, DJ .

CIRCULATION, 2006, 113 (08) :1140-1150

[3]

Pharmacological activation of liver X receptors promotes reverse cholesterol transport in vivo [J].

Naik, SU ;

Wang, X ;

Da Silva, JS ;

Jaye, M ;

Macphee, CH ;

Reilly, MP ;

Billheimer, JT ;

Rothblat, GH ;

Rader, DJ .

CIRCULATION, 2006, 113 (01) :90-97

[4]

The beneficial effects of lipid-lowering drugs beyond lipid-lowering effects: A comparative study with pravastatin, atorvastatin, and fenofibrate in patients with type IIa and type IIb hyperlipidemia [J].

Saklamaz, A ;

Comlekci, A ;

Temiz, A ;

Caliskan, S ;

Ceylan, C ;

Alacacioglu, A ;

Yesil, S .

METABOLISM-CLINICAL AND EXPERIMENTAL, 2005, 54 (05) :677-681

[5]

Nicotinic acid in the management of dyslipidaemia associated with diabetes and metabolic syndrome: a position paper developed by a European Consensus Panel [J].

Shepherd, J ;

Betteridge, J ;

Van Gaal, L .

CURRENT MEDICAL RESEARCH AND OPINION, 2005, 21 (05) :665-682

[6]

Current understanding of the metabolism and biological actions of HDL [J].

von Eckardstein, A ;

Hersberger, M ;

Rohrer, L .

CURRENT OPINION IN CLINICAL NUTRITION AND METABOLIC CARE, 2005, 8 (02) :147-152

[7]

Biologic therapies for dyslipidemia [J].

Davidson M.H. .

Current Atherosclerosis Reports, 2004, 6 (1) :69-72

[8]

The role of high-density lipoprotein (HDL) cholesterol in the prevention and treatment of coronary heart disease: Expert group recommendations [J].

Sacks, FM .

AMERICAN JOURNAL OF CARDIOLOGY, 2002, 90 (02) :139-+

← 1 →