缺血性脑卒中患者血浆同型半胱氨酸(Hcy)的相关性研究

被引：9

作者：

刘丹

朱木林

袁云华

机构：

[1] 四川省泸州市人民医院神经内科

来源：

医学理论与实践 | 2014年 / 27卷 / 02期

关键词：

缺血性脑卒中; 血浆同型半胱氨酸;

D O I：

10.19381/j.issn.1001-7585.2014.02.011

中图分类号：

R743.3 [急性脑血管疾病（中风）];

学科分类号：

100204 [神经病学];

摘要：

<正>缺血性脑卒中具有高发病率和死亡率,是研究最深入的疾病之一,在现有治疗方法下,控制多种危险因素成为降低脑卒中发生率、致残率、致死率的最佳途径。既往发现的传统危险因素已不能完全诠释脑血管疾病发生的机制,因此发现更多的危险因素及其对脑血管疾病的影响机制,成为更多学者面临的问题和挑战。目前血浆Hcy水平与脑卒中的相关性存在争议,本文通过总结缺血性脑卒中患者同

引用

页码：164 / 165+176 +176

页数：3

共 17 条

[1]

Acute phase homocysteine related to severity and outcome of atherothrombotic stroke [J].

Wu, Xu-Qing ;

Ding, Jing ;

Ge, An-Yan ;

Liu, Fei-Feng ;

Wang, Xin ;

Fan, Wei .

EUROPEAN JOURNAL OF INTERNAL MEDICINE, 2013, 24 (04) :362-367

[2]

Novel alleles of 31-bp VNTR polymorphism in the human cystathionine β-synthase (CBS) gene were detected in healthy Asians [J].

Gan, Yik-Yuen ;

Chen, Chuan-Fei .

JOURNAL OF GENETICS, 2010, 89 (04) :449-455

[3]

Association of a Common Polymorphism in the Methylenetetrahydrofolate Reductase (MTHFR) Gene With Bone Phenotypes Depends on Plasma Folate Status.[J].Robert RMcLean;DavidKarasik;JacobSelhub;Katherine LTucker;Jose MOrdovas;Giuseppina TRusso;L AdrienneCupples;Paul FJacques;Douglas PKiel.J Bone Miner Res.2009, 3

[4]

Homocystine Levels, Polymorphisms and the Risk of Ischemic Stroke in Young Asian Indians [J].

Biswas, Arijit ;

Ranjan, Ravi ;

Meena, Arvind ;

Akhter, Mohammad Suhail ;

Yadav, Birendra Kumar ;

Munisamy, Murali ;

Subbiah, Vivekanandhan ;

Behari, Madhuri ;

Saxena, Renu .

JOURNAL OF STROKE & CEREBROVASCULAR DISEASES, 2009, 18 (02) :103-110

[5]

Are plasma homocysteine levels related to neurological severity and functional outcome after ischemic stroke in the Korean population?.[J].In-Uk Song;Joong-Seok Kim;Seon-Young Ryu;Sang-Bong Lee;Seung-Jae Lee;Du-shin Jeong;Yeong-In Kim;Kwang-Soo Lee.Journal of the Neurological Sciences.2008, 1

[6]

Efficacy of folic acid supplementation in stroke prevention: a meta-analysis [J].

Wang, Xiaobin ;

Qin, Xianhui ;

Demirtas, Hakan ;

Li, Jianping ;

Mao, Guangyun ;

Huo, Yong ;

Sun, Ningling ;

Liu, Lisheng ;

Xu, Xiping .

LANCET, 2007, 369 (9576) :1876-1882

[7]

Acute hyperhomocysteinemia induces microvascular and macrovascular endothelial dysfunction [J].

Abahji, Thomas N. ;

Nill, Lars ;

Ide, Nagatoshi ;

Keller, Christiane ;

Hoffmann, Ulrich ;

Weiss, Norbert .

ARCHIVES OF MEDICAL RESEARCH, 2007, 38 (04) :411-416

[8]

Common genetic variants of homocysteine metabolism in ischemic stroke: a case–control study.[J]..European Journal of Neurology.2005, 8

[9]

Elevated plasma homocysteine in acute stroke was not associated with severity and outcome: stronger association with small artery disease [J].

Perini, F ;

Galloni, E ;

Bolgan, I ;

Bader, G ;

Ruffini, R ;

Arzenton, E ;

Alba, S ;

Azzini, C ;

Bartolomei, L ;

Billo, G ;

Bortolon, F ;

Dudine, P ;

Garofalo, PG ;

L'Erario, R ;

Morra, M ;

Parisen, P ;

Stenta, G ;

Toso, V .

NEUROLOGICAL SCIENCES, 2005, 26 (05) :310-318

[10]

Serum total homocysteine concentrations and risk of stroke and its subtypes in Japanese [J].

Iso, H ;

Moriyama, Y ;

Sato, S ;

Kitamura, A ;

Tanigawa, T ;

Yamagishi, K ;

Imano, H ;

Ohira, T ;

Okamura, T ;

Naito, Y ;

Shimamoto, T .

CIRCULATION, 2004, 109 (22) :2766-2772

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