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An epidermal growth factor inhibitor, Gefitinib, induces apoptosis through a p53-dependent upregulation of pro-apoptotic molecules and downregulation of anti-apoptotic molecules in human lung adenocarcinoma A549 cells[J] . Gee-Chen Chang,Chang-Tze Ricky Yu,Ching-Hwa Tsai,Jia-Rong Tsai,Jen-Chi Chen,Chun-Chi Wu,Wen-Jun Wu,Shih-Lan Hsu.European Journal of Pharmacology . 2008 (1)