缺血引发的脑损伤发病学机理

被引：7

作者：

王梅

王友群

机构：

[1] 中国药科大学药理研究室

来源：

中国实用医药 | 2008年 / 25期

关键词：

脑缺血; 损伤机制;

D O I：

10.14163/j.cnki.11-5547/r.2008.25.138

中图分类号：

R741 [神经病学];

学科分类号：

摘要：

脑缺血疾病是目前严重危害人类健康的主要疾病之一,具有发病率高、致残率高、死亡率高的特点。所以日益受到政府和学界的重视。脑缺血后可以引起一系列病理生理和生化方面的改变,目前公认的脑缺血损伤机制包括:兴奋性损害、Ca2+超载、自由基及脂质过氧化、线粒体功能障碍、NO、细胞因子、立早基因和热休克蛋白表达紊乱、细胞凋亡等。

引用

页码：183 / 186

页数：4

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