以HRP及氚水作示踪剂研究脑脊液的回流途径

被引：1

作者：

董剑平

孙善全

机构：

[1] 重庆医科大学解剖学教研室

来源：

解剖学报 | 1999年 / 03期

关键词：

脑脊液循环,脑室周围器官,鼻粘膜下组织间隙,嗅丝周围间隙;

D O I：

10.16098/j.issn.0529-1356.1999.03.008

中图分类号：

学科分类号：

摘要：

目的研究脑脊液（ＣＳＦ）的正常回流途径。方法将ＨＲＰ、氚水作为示踪剂分别缓慢注入两组大白鼠侧脑室。应用光、电镜技术和液闪、放射自显影技术对ＨＲＰ和氚水在脑组织中分布状况进行观察。结果在脑室周围器官及脑室周围室管膜、软脑膜层有ＨＲＰ反应产物的聚集，在鼻中隔的鼻粘膜下组织间隙、嗅丝周围间隙及静脉周围和管腔内也可见到ＨＲＰ反应产物；液闪计数显示，大白鼠的脉络丛、脑垂体、最后区、松果体等脑室周围器官放射性活度明显高于本底；放射自显影显示大白鼠脑组织神经层细胞内有散在分布的银颗粒。结论ＣＳＦ可经由脑室周围器官、脑膜及鼻粘膜下静脉网汇入体循环，同时ＣＳＦ可回流至大脑神经细胞层，参与形成神经细胞层组织液，与维持脑的正常功能有关。

引用

页码：29 / 32+104

页数：5

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