应用傅立叶变换红外光谱研究白血病骨髓血红细胞

被引:10
作者
高体玉
慈云祥
付爽
王德炳
机构
[1] 北京大学化学与分子工程学院!北京
[2] 不详
[3] 北京大学医学院血液病研究所!北京
基金
中国博士后科学基金;
关键词
傅立叶变换红外光谱; 白血病; 骨髓红细胞;
D O I
10.13209/j.0479-8023.2001.036
中图分类号
O657.3 [光化学分析法(光谱分析法)]; O629 [天然化合物];
学科分类号
摘要
研究了急性粒细胞白血病 (AML)和慢性粒细胞白血病 (CML)患者的骨髓血红细胞的红外光谱差异性 :与CML红细胞相比 ,AML红细胞酰胺Ⅰ带较宽 ;1540cm- 1与 10 84cm- 1吸收峰面积之间的比值较低 ,范围较窄。该结果提示AML和CML骨髓血红细胞系中有核红细胞的数量分布不同 ,同时提示骨髓红细胞的成熟可能与白血病细胞的增殖有关。骨髓血细胞的红外光谱的差异性对白血病的分析和评价具有重要的意义
引用
收藏
页码:192 / 196
页数:5
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