肝纤维化基础和临床研究热点问题

被引:14
作者
陆伦根
机构
[1] 上海交通大学附属第一人民医院消化科
关键词
肝纤维化; 基础研究; 诊断; 治疗;
D O I
暂无
中图分类号
R575.2 [肝硬变];
学科分类号
100201 [内科学];
摘要
<正>肝纤维化是各类损伤因子累及肝脏后的一种病理修复状态。几乎任何能造成肝脏损害的因素均可致肝脏发生纤维化。在这个病理进程中,正常功能肝细胞数量的减少、肝脏小叶结构改变、血液循环紊乱等均可致肝脏正常生理功能逐步丧失,最终进展为肝硬化。业已形成的肝纤维化甚至肝硬化能否改善乃至逆转是目前肝纤维化研究领域的关键。以往的动物模型和近期临床领域充分的研究证据支持肝纤维化/肝硬化能够被逆转。Marcellin et al
引用
收藏
页码:1 / 3
页数:3
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