低浓度环氧丙烷的细胞遗传学效应研究附视频

被引:10
作者
李明
陈彦文
徐敏秋
李梦燕
王立言
张吉
李玉杰
于秀兰
刘积善
机构
[1] 锦化化工公司职业病防治所!葫芦岛市
[2] 葫芦岛市职业病防治所
[3] 辽宁省劳动卫生职业病防治所
[4] 辽宁省劳动卫生职业
关键词
环氧丙烷; 染色体畸变; 微核; 姐妹染色单体交换;
D O I
10.13692/j.cnki.gywsyzyb.2000.04.005
中图分类号
R99 [毒物学(毒理学)];
学科分类号
100405 ;
摘要
为探讨低浓度环氧丙烷的细胞遗传学效应 ,对 46名环氧丙烷作业工人和 74名对照工人外周血淋巴细胞染色体畸变、微核、姐妹染色单体交换进行了检测分析。结果表明 ,环氧丙烷接触组工人外周血淋巴细胞姐妹染色单体交换率显著高于对照组 ,而染色体畸变率和微核率两组间均无显著性差异 ,提示低浓度环氧丙烷具有细胞遗传学毒性 ,可导致DNA损伤
引用
收藏
页码:204 / 206
页数:3
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