抗8-AG和HGPRT缺失的人早幼粒白血病细胞突变株(HL-60-AR)的体外诱导分化潜能

被引：6

作者：

刘友华

薛社普

机构：

[1] 中国医学科学院基础医学研究所,中国医学科学院基础医学研究所北京,北京

来源：

中国医学科学院学报 | 1986年 / 06期

关键词：

人早幼粒白血病细胞(HL-60); 细胞分化; HGPRT-突变株;

D O I：

暂无

中图分类号：

学科分类号：

摘要：

具有抗8-AG和HGPRT-遗传标记的HL-60-AR细胞与维生素A酸或二甲基亚砜一起保温后,细胞对NBT还原反应能力增强;细胞膜表面出现C2补体受体;细胞形态按粒系白细胞途径向较成熟的方向发育。同时,细胞并合3H-TdR的速率降低;细胞几乎全部丧失在软琼脂中形成集落的能力。HL-60-AR细胞对次黄嘌呤的诱导分化反应不敏感。

引用

页码：461 / 465+507 +507-508

页数：7

共 10 条

[1]

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[2]

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实验生物学报, 1985, (04) :389-404

[6] 抗8-AG和HGPRT缺失的人早幼粒白血病细胞突变株(HL-60-AR)的建立 [J].

刘友华 ;

田竞生 ;

徐炎 ;

薛社普 .

中国医学科学院学报, 1986, (06) :456-460+505

[7]

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