体外冲击波碎石前后机体内皮素的变化和钙离子拮抗剂对肾损害的防护作用

被引:3
作者
孟庆军
周惜才
章咏裳
叶荣骧
机构
[1] 河南医科大学附属第一院泌尿外科
[2] 同济医科大学同济医院
[3] 同济医科大学同济医院 郑州
关键词
体外冲击波碎石术; 内皮素; 肾损害; 异搏定;
D O I
暂无
中图分类号
R691.4 [泌尿生殖系结石及异物];
学科分类号
1002 ; 100210 ;
摘要
将36只家兔随机分为三组,A组:15只,未用异搏定;B组:15只,异搏定处理;C组:6只,正常对照。A和B组予体外冲击波碎石(ESWL),观察ESWL前后血、尿和肾组织中内皮素的变化。结果A组ESWL后1、3天尿和肾组织中内皮素显著升高,B组ESWL后1天尿内皮素轻度升高,而两组血中内皮素无明显变化。提示ESWL后早期机体内皮素升高可能与肾损害有关,异搏定可抑制内皮素的升高,减轻肾损害。
引用
收藏
页码:352 / 353+393 +393-394
页数:4
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