膝关节骨关节炎患者滑液中一氧化氮的动态变化及其临床意义

被引:12
作者
彭丹
孙材江
陈游
机构
[1] 湖南医科大学第二附属医院!湖南长沙
关键词
骨关节炎; 一氧化氮; 氧自由基; 滑液;
D O I
暂无
中图分类号
R684.3 [关节炎];
学科分类号
1002 ; 100210 ;
摘要
目的检测膝关节骨关节炎(OA)各期患者滑液中一氧化氮(NO)和过氧化脂质(LPO)水平,分析并探讨其临床意义。方法选择符合诊断标准各期膝骨关节炎患者的关节滑液,用镀铜镉还原法及TBA荧光法分别进行NO及LPO的测定。结果骨关节炎患者各期NO含量不同,以中期最高,而LPO在各期中有所升高,在晚期与NO出现分离现象。结论NO参加骨关节炎中软骨损害的全过程。 NO可用作判断OA中关节炎软骨损害的重要指标之一。
引用
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页码:1192 / 1193
页数:2
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