金天格胶囊对成骨细胞作用的研究

被引：26

作者：

张依山

机构：

[1] 河南省郑州市骨科医院骨质疏松科

来源：

现代生物医学进展 | 2008年 / 02期

关键词：

骨质疏松; 金天格胶囊; 成骨细胞;

D O I：

10.13241/j.cnki.pmb.2008.02.031

中图分类号：

R285 [中药药理学];

学科分类号：

摘要：

目的:观察金天格胶囊对成骨细胞的直接刺激作用。方法:采用酶消化法分离培养成骨细胞,加入不同浓度的金天格胶囊药液,测定碱性磷酸酶(AKP)、骨钙素(BGP)和尿液吡啶酚(PYD)的含量。结果:AKP、BGP水平随药物浓度增加而升高,PYD反而减少(P<0.05)。结论:金天格胶囊对成骨细胞有直接刺激作用;对破骨细胞也有抑制作用。

引用

页码：321 / 322

页数：2

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