急性冠状动脉综合征PCI术后抗栓治疗进展

被引:9
作者
刘宏斌
机构
[1] 解放军总医院南楼临床部心血管内二科
关键词
急性冠状动脉综合征; PCI术; 抗血小板治疗; 抗凝治疗; 药物抵抗;
D O I
暂无
中图分类号
R541.4 [冠状动脉(粥样)硬化性心脏病(冠心病)];
学科分类号
摘要
<正>冠心病是一类严重危害人类健康的疾病,近年来,急性冠状动脉综合征(ACS)的发病率和病死率呈明显上升趋势,而动脉粥样硬化斑块破裂、血栓形成、管腔闭塞是急性冠状动脉综合征主要发病机制。随着急性心肌梗死实施再灌注治疗技术的开展,尤其是经皮冠状动脉介入手术(PCI)的实施,使得患者的预后及生活质量得到了较大程度的提高。但是目前仍然存在严重问题,即术后支架内血栓形成或再狭窄,可能与支架种类、置入技术方法、冠状动脉病变特点及机体状况、过早停用双联抗血小板药物、药物抵抗等因素有关。如何预防并积极实施合理抗
引用
收藏
页码:1 / 3
页数:3
相关论文
共 7 条
[1]  
Oral anticoagulation and antiplatelets in atrial fibrillation patients after myocardial infarction and coronary intervention[J] . Morten Lamberts,Gunnar H. Gislason,Jonas Bjerring Olesen,S?ren Lund Kristensen,Anne-Marie Schjerning Olsen,Anders Mikkelsen,Christine Benn Christensen,Gregory Y.H. Lip,Lars K?ber,Christian Torp-Pedersen,Morten Lock Hansen.Journal of the American College of Cardiology . 2013
[2]   Efficacy and safety of argatroban with or without glycoprotein IIb/IIIa inhibitor in patients with heparin induced thrombocytopenia undergoing percutaneous coronary intervention for acute coronary syndrome [J].
Cruz-Gonzalez, Ignacio ;
Sanchez-Ledesma, Maria ;
Baron, Suzanne J. ;
Healy, Josephine L. ;
Watanabe, Hikari ;
Osakabe, Masanori ;
Yeh, Robert W. ;
Jang, Ik-Kyung .
JOURNAL OF THROMBOSIS AND THROMBOLYSIS, 2008, 25 (02) :214-218
[3]  
Reduced 6-month resource use and costs associated with cilostazol in patients after successful coronary stent implantation: Results from the Cilostazol for RESTenosis (CREST) trial[J] . Zefeng Zhang,Jovonne K. Foster,Paul Kolm,Claudine T. Jurkovitz,Karen M. Parker,Nancy V. Murrah,Grant T. Anderson,John S. Douglas,William S. Weintraub.American Heart Journal . 2006 (4)
[4]   Bivalirudin versus heparin and glycoprotein IIb/IIIa inhibition among patients with renal impairment undergoing percutaneous coronary intervention (A subanalysis of the REPLACE-2 trial) [J].
Chew, DP ;
Lincoff, AM ;
Gurm, H ;
Wolski, K ;
Cohen, DJ ;
Henry, T ;
Feit, F ;
Topol, EJ .
AMERICAN JOURNAL OF CARDIOLOGY, 2005, 95 (05) :581-585
[5]  
Coronary syndromes following aspirin withdrawal[J] . Emile Ferrari,Mustapha Benhamou,Pierre Cerboni,Baudouy Marcel.Journal of the American College of Cardiology . 2005 (3)
[6]   Intravenous glycoprotein IIb/IIIa receptor antagonists reduce mortality after percutaneous coronary interventions [J].
Karvouni, E ;
Katritsis, DG ;
Ioannidis, JPA .
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 2003, 41 (01) :26-32
[7]  
Effects of pretreatment with clopidogrel and aspirin followed by long-term therapy in patients undergoing percutaneous coronary intervention: the PCI-CURE study[J] . Shamir R Mehta,Salim Yusuf,Ron JG Peters,Michel E Bertrand,Basil S Lewis,Madhu K Natarajan,Klas Malmberg,Hans-Jürgen Rupprecht,Feng Zhao,Susan Chrolavicius,Ingrid Copland,Keith AA Fox.The Lancet . 2001 (9281)