亚胺培南联合氨溴索对重症肺炎炎症因子及临床疗效影响

被引：20

作者：

陈军

芮晓艳

张艳喜

丁婷婷

范洪峰

机构：

[1] 滁州市第一人民医院安徽医科大学滁州临床学院呼吸科

来源：

现代生物医学进展 | 2017年 / 17卷 / 06期

基金：

安徽省自然科学基金;

关键词：

亚胺培南; 氨溴索; 重症肺炎; 血清降钙素原; 白介素-10;

D O I：

10.13241/j.cnki.pmb.2017.06.019

中图分类号：

R563.1 [肺炎];

学科分类号：

100201 [内科学];

摘要：

目的:探讨亚胺培南联合氨溴索对重症肺炎患者血清降钙素原(PCT),白介素-10(IL-10)及临床疗效的影响研究。方法:收集我院收治的100例重症肺炎患者机分为实验组和对照组,每组50例。对照组患者在基础治疗的基础上给予氨溴索治疗,实验组患者在对照组基础上给予亚胺培南治疗。观察并比较两组患者白细胞(WBC)、血清PCTJL-10水平以及患者的临床治疗有效率。结果:与治疗前相比,两组患者的WBC、PCT、IL-10水平均下降差异具有统计学意义(P<0.05);与对照组相比,实验组患者的WBC、PCT、IL-10水平较低差异具有统计学意义(P<0.05);与对照组相比,实验组患者的临床治疗有效率较高,差异具有统计学意义(P<0.05)。结论:亚胺培南联合氨溴索能够降低重症肺炎患者WBC、PCT、IL-10水平,临床疗效较好,提高了治疗效果。

引用

页码：1076 / 1078+1082 +1082

页数：4

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