磁共振T1ρ技术定量检测椎间盘早期退变的初步研究

被引：24

作者：

王伟 ^{[1
]}

Queenie Chan ^{[2
]}

梁文 ^{[1
]}

陈玲 ^{[1
]}

杨建明 ^{[1
]}

全显跃 ^{[1
]}

机构：

[1] 南方医科大学珠江医院影像诊断科

[2] 飞利浦医疗保健事业部

来源：

中国医学影像学杂志 | 2013年 / 21卷 / 06期

基金：

广东省科技计划;

关键词：

脊柱疾病; 椎间盘退变; 磁共振成像;

D O I：

暂无

中图分类号：

R681.5 [脊柱及背疾病];

学科分类号：

100220 [骨科学];

摘要：

目的探讨3.0T磁共振T1ρ定量技术检测在体椎间盘早期退变的价值。资料与方法35名健康志愿者(男16名,女19名)在3.0TMRI上采集常规T2WI及T1ρ图像,对椎间盘进行Pfirrmann分级及髓核T1ρ值测定,分析T1ρ值与Pfirrmann分级、节段、性别的关系。结果 T1ρ值与Pfirrmann分级呈显著负相关(r=-0.542,P<0.001);L5/S1节段T1ρ值为(94.80±26.60)ms,显著低于L2/L3的(117.18±25.64)ms和L3/L4的(115.52±28.53)ms(P<0.01),其余节段无显著差异(P>0.05);各节段T1ρ值无性别差异(t=0.006、0.042、0.797、1.022、0.038,P>0.05)。结论 T1ρ弛豫时间与椎间盘退变程度密切相关,T1ρ成像可以作为客观、敏感地检测椎间盘早期退变的有效手段。

引用

页码：406 / 410

页数：5

共 10 条

[1]

T1ρ Magnetic Resonance Imaging Quantification of Early Lumbar Intervertebral Disc Degeneration in Healthy Young Adults [J].

Zobel, Bruno Beomonte ;

Vadala, Gianluca ;

Del Vescovo, Riccardo ;

Battisti, Sofia ;

Martina, Francesca Maria ;

Stellato, Luigi ;

Leoncini, Emanuele ;

Borthakur, Arijitt ;

Denaro, Vincenzo .

SPINE, 2012, 37 (14) :1224-1230

[2]

T1ρ Magnetic Resonance Imaging and Discography Pressure as Novel Biomarkers for Disc Degeneration and Low Back Pain [J].

Borthakur, Arijitt ;

Maurer, Philip M. ;

Fenty, Matthew ;

Wang, Chenyang ;

Berger, Rachelle ;

Yoder, Jonathon ;

Balderston, Richard A. ;

Elliott, Dawn M. .

SPINE, 2011, 36 (25) :2190-2196

[3]

The Effects of Age, Sex, Ethnicity, and Spinal Level on the Rate of Intervertebral Disc Degeneration A Review of 1712 Intervertebral Discs [J].

Siemionow, Krzysztof ;

An, Howard ;

Masuda, Koichi ;

Andersson, Gunnar ;

Cs-Szabo, Gabriella .

SPINE, 2011, 36 (17) :1333-1339

[4]

What is intervertebral disc degeneration, and what causes it? [J].

Adams, Michael A. ;

Roughley, Peter J. .

SPINE, 2006, 31 (18) :2151-2161

[5]

Assessment of Human Disc Degeneration and Proteoglycan Content Using T1ρ-weighted Magnetic Resonance Imaging.[J].Wade Johannessen;Joshua D. Auerbach;Andrew J. Wheaton;Alykhan Kurji;Arijitt Borthakur;Ravinder Reddy;Dawn M. Elliott.Spine.2006, 11

[6]

In vivo quantification of human lumbar disc degeneration using T1ρ-weighted magnetic resonance imaging.[J].Joshua D. Auerbach;Wade Johannessen;Arijitt Borthakur;Andrew J. Wheaton;Carol A. Dolinskas;Richard A. Balderston;Ravinder Reddy;Dawn M. Elliott.European Spine Journal.2006, 3S

[7]

Chapter 4European guidelinesfor the management of chronicnonspecific low back pain.[J].O. Airaksinen;J. I. Brox;C. Cedraschi;J. Hildebrandt;J. Klaber-Moffett;F. Kovacs;A. F. Mannion;S. Reis;J. B. Staal;H. Ursin;G. Zanoli.European Spine Journal.2006, 2

[8]

Magnetic resonance classification of lumbar intervertebral disc degeneration [J].