调节性T细胞与炎症性肠病

被引：5

作者：

罗晓婷

刘懿

机构：

[1] 华山医院消化科

来源：

国际消化病杂志 | 2011年 / 31卷 / 02期

关键词：

调节性T细胞; 炎症性肠病; 克罗恩病; 溃疡性结肠炎;

D O I：

暂无

中图分类号：

R574 [肠疾病];

学科分类号：

100201 [内科学];

摘要：

炎症性肠病(IBD)的病因和发病机制尚未完全明确,肠道黏膜免疫系统对肠道非致病抗原的异常反应所导致的炎症过程在发病中起重要作用。调节性T细胞(Treg)有抑制自身免疫的功能,是维持肠道免疫稳态的重要因素。Treg功能紊乱致免疫耐受被打破可能是导致人类IBD的原因之一。此文就目前国内外关于Treg在IBD的发病机制中的研究现状及指导治疗的方向作一综述。

引用

收藏

页码：63 / 67

页数：5

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