Cre/lox系统介导的位点特异性重组技术及其应用

被引:6
作者
李卫
郭光沁
郑国锠
机构
[1] 兰州大学细胞生物学研究所!兰州
关键词
Cre/lox; 定点整合; 特定基因删除; 诱变; 基因克隆;
D O I
10.13560/j.cnki.biotech.bull.1985.2000.01.007
中图分类号
Q784 [基因的重组];
学科分类号
摘要
Cre/lox系统是源于P1噬菌体的一个DNA重组体系,它能导致在特定的DNA序列(loxP位点)处发生定点重组。该系统可以将外源基因定点整合到染色体上或将特定DNA片段删除;这种定位重组系统在遗传操作中发挥了重要的作用。
引用
收藏
页码:36 / 40
页数:5
相关论文
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