氧化应激与线粒体功能障碍和胰岛素抵抗的关系

被引:17
作者
周红坚 [1 ]
周园媛 [2 ]
机构
[1] 云南省玉溪市人民医院老年病科
[2] 河北医科大学第三医院内分泌一科
关键词
D O I
暂无
中图分类号
R587.1 [糖尿病];
学科分类号
100201 [内科学];
摘要
<正>胰岛素抵抗(IR)是指正常浓度的胰岛素生理效应低于正常,主要表现为胰岛素作用的靶器官或组织(主要是肝脏、肌肉和脂肪)对胰岛素作用的敏感性及反应性降低,是导致肥胖、代谢综合征、非酒精性脂肪肝、2型糖尿病及其并发症和心血管类疾病的主要病因。目前,越来越多的证据表明氧化应激可诱导线粒体功能障碍、胰岛β细胞功能障碍,并最终导致糖尿
引用
收藏
页码:17 / 19
页数:3
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